Meet the Real-Life Loves of theGrey's AnatomyCast (Including One Couple Who Met on Set!)

Mar. 15, 2025

Ellen Pompeo and Chris Ivery attend the 2025 Vanity Fair Oscar Party on March 2, 2025, in Beverly Hills, Calif. ; Matthew Alan and Camilla Luddington attend the 2025 WWD Style Awards on Jan. 3, 2025, in Los Angeles ; Patrick Dempsey and Jillian Fink attend the CHANEL and Charles Finch Annual Pre-Oscar Dinner on March 1, 2025, in Beverly Hills, Calif.Photo:Jamie McCarthy/WireImage ; Stefanie Keenan/WWD via Getty ; Jon Kopaloff/WireImage

Jamie McCarthy/WireImage ; Stefanie Keenan/WWD via Getty ; Jon Kopaloff/WireImage

Grey’s Anatomyis just as much a show about love as it is a medical drama. But off-screen, many of the cast members have love stories of their own.With 21 seasons and counting, the ABC series has delivered no shortage of both romance and heartbreak, as viewers have watched countless couples break up and make up within the halls of Grey Sloan Memorial Hospital. From Derek Shepherd and Meredith Grey’s iconic Post-It note vows to Jackson Avery’s jaw-dropping love confession to April Kepner during her wedding, the show has delivered some of television’s most unforgettable romantic storylines.Meredith’s famous “pick me, choose me” line might’veinspired a Gen-Z trend(the “pick me girl”), but in real life,Ellen Pompeo— whobid farewell to the showafter a 19-season run but remains a recurring guest — has been married to her husbandChris Iverysince 2007.Pompeo’s castmates' love lives are also far less dramatic than their characters but just as sweet (and long-lasting!).James Pickens Jr. wed his wife in 1984, whileCamilla Luddingtonmarried her husbandMatthew Alanin August 2019.From a couple who met on set to two who have been married for over 40 years, here are the real-life loves of the cast ofGrey’s Anatomy.

Grey’s Anatomyis just as much a show about love as it is a medical drama. But off-screen, many of the cast members have love stories of their own.

With 21 seasons and counting, the ABC series has delivered no shortage of both romance and heartbreak, as viewers have watched countless couples break up and make up within the halls of Grey Sloan Memorial Hospital. From Derek Shepherd and Meredith Grey’s iconic Post-It note vows to Jackson Avery’s jaw-dropping love confession to April Kepner during her wedding, the show has delivered some of television’s most unforgettable romantic storylines.

Meredith’s famous “pick me, choose me” line might’veinspired a Gen-Z trend(the “pick me girl”), but in real life,Ellen Pompeo— whobid farewell to the showafter a 19-season run but remains a recurring guest — has been married to her husbandChris Iverysince 2007.

Pompeo’s castmates' love lives are also far less dramatic than their characters but just as sweet (and long-lasting!).James Pickens Jr. wed his wife in 1984, whileCamilla Luddingtonmarried her husbandMatthew Alanin August 2019.

From a couple who met on set to two who have been married for over 40 years, here are the real-life loves of the cast ofGrey’s Anatomy.

01of 22Ellen Pompeo & Chris IveryEllen Pompeo and Chris Ivery attend the 2018 Vanity Fair Oscar Party Hosted By Radhika Jones - Arrivals at Wallis Annenberg Center for the Performing Arts on March 4, 2018, in Beverly Hills, Calif.Presley Ann/Patrick McMullan via GettyWhen Ellen Pompeo hangs up Meredith Grey’s scrubs, she goes home to her husband of almost two decades: Chris Ivery. The pair met in 2003, but it wasn’t “a love at first sight” story.During a December 2022 appearance onThe Drew Barrymore Show, Pompeo explained that she met Ivery while in a grocery store, where he knew a friend that she was with.“It’s not some big romance that happened over crackers and cheese in the aisle,” she said, explaining that they said a quick hello before having some heated exchanges down the line.“He called me a bunch of times and I wouldn’t call him back. Then he said, ‘You’re rude. You won’t call me back,’ and I said, ‘Well because I’m not trying to go on a date with you,’ " Pompeo recalled. “We had a fight first. That’s kind of always the way to my heart, piss me off and I’m all yours.“Pompeo and Ivery got married in 2007 and later welcomed three children — Stella Luna, Sienna May and Eli Christopher, born in 2009, 2014 and 2016, respectively.Though Pompeo has called her supportive husband “my rock … my soulmate,” the record producer wasn’t always keen on her steamy love scenes onGrey’s.“I remember in the beginning it was really hard for him,” she said on theLadies First with Laura Brownpodcast in 2021. “He was like, ‘This is not what I signed up for. You go to work and make out with that. I like Patrick [Dempsey] and everything, he’s a good dude, but like really?’ "

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Ellen Pompeo & Chris Ivery

Ellen Pompeo and Chris Ivery attend the 2018 Vanity Fair Oscar Party Hosted By Radhika Jones - Arrivals at Wallis Annenberg Center for the Performing Arts on March 4, 2018, in Beverly Hills, Calif.Presley Ann/Patrick McMullan via Getty

When Ellen Pompeo hangs up Meredith Grey’s scrubs, she goes home to her husband of almost two decades: Chris Ivery. The pair met in 2003, but it wasn’t “a love at first sight” story.

During a December 2022 appearance onThe Drew Barrymore Show, Pompeo explained that she met Ivery while in a grocery store, where he knew a friend that she was with.

“It’s not some big romance that happened over crackers and cheese in the aisle,” she said, explaining that they said a quick hello before having some heated exchanges down the line.

“He called me a bunch of times and I wouldn’t call him back. Then he said, ‘You’re rude. You won’t call me back,’ and I said, ‘Well because I’m not trying to go on a date with you,’ " Pompeo recalled. “We had a fight first. That’s kind of always the way to my heart, piss me off and I’m all yours.”

Pompeo and Ivery got married in 2007 and later welcomed three children — Stella Luna, Sienna May and Eli Christopher, born in 2009, 2014 and 2016, respectively.

Though Pompeo has called her supportive husband “my rock … my soulmate,” the record producer wasn’t always keen on her steamy love scenes onGrey’s.

“I remember in the beginning it was really hard for him,” she said on theLadies First with Laura Brownpodcast in 2021. “He was like, ‘This is not what I signed up for. You go to work and make out with that. I like Patrick [Dempsey] and everything, he’s a good dude, but like really?’ "

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Camilla Luddington & Matthew Alan

Camilla Luddington knows a thing or two about longtime loves as Dr. Jo Wilson inGrey’s Anatomy— much like her real-life romance with her husband Matthew Alan, who is a fellow actor known for his role in13 Reasons Why.

She added, “To be honest, I’m just excited to get into that new normal of married life.”

The pair havetwo kids:daughter Hayden Alan, born in April 2017, and sonLucas Matthew, welcomed in August 2020.

03of 22Caterina ScorsoneCaterina Scorsone attends the 2024 People’s Choice Awards at Barker Hangar on February 18, 2024 in Santa Monica, California.Monica Schipper/Getty ImagesCaterina Scorsone, who plays Amelia Shepherd, split from her husband of 10 years, Rob Giles, in 2020.“Caterina and Rob have separated,” their reps told PEOPLE at the time. “They remain friends and are committed to co-parentingtheir children in a spirit of love.“The actress wed Giles, a musician, in 2009. They share three daughters:Eliza,Paloma “Pippa” MichaelaandArwen.

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Caterina Scorsone

Caterina Scorsone attends the 2024 People’s Choice Awards at Barker Hangar on February 18, 2024 in Santa Monica, California.Monica Schipper/Getty Images

Monica Schipper/Getty Images

Caterina Scorsone, who plays Amelia Shepherd, split from her husband of 10 years, Rob Giles, in 2020.

“Caterina and Rob have separated,” their reps told PEOPLE at the time. “They remain friends and are committed to co-parentingtheir children in a spirit of love.”

The actress wed Giles, a musician, in 2009. They share three daughters:Eliza,Paloma “Pippa” MichaelaandArwen.

04of 22Christopher Carmack & Erin SlaverChris Carmack and his wife, Erin Slaver.Stewart Cook via GettyChris Carmack— who plays orthopedic surgeon and heartthrob Atticus “Link” Lincoln on the medical drama — married his longtime girlfriendErin Slaverin 2018.“Chris and I areoverjoyed to now be husband and wife!” Slaver told PEOPLE of their special day. “The wedding, although a blur, couldn’t have been a more perfect beginning to the adventure that lies ahead for our family.“The pair have a band together — Life on Eris — and released their debut EP,Stonewall, in October 2020.The pair share two daughters: Kai, born in 2016, andCielle Estee, welcomed in 2022.

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Christopher Carmack & Erin Slaver

Chris Carmack and his wife, Erin Slaver.Stewart Cook via Getty

Chris Carmack— who plays orthopedic surgeon and heartthrob Atticus “Link” Lincoln on the medical drama — married his longtime girlfriendErin Slaverin 2018.

“Chris and I areoverjoyed to now be husband and wife!” Slaver told PEOPLE of their special day. “The wedding, although a blur, couldn’t have been a more perfect beginning to the adventure that lies ahead for our family.”

The pair have a band together — Life on Eris — and released their debut EP,Stonewall, in October 2020.

The pair share two daughters: Kai, born in 2016, andCielle Estee, welcomed in 2022.

05of 22Kim Raver & Manu BoyerManu Boyer and Kim Raver attend Lifetime’s Female Directors and Leading Actresses 2019 Winter Television Critics Association Press Tour at The Langham Huntington on Feb. 10, 2019, in Pasadena, Calif.Jesse Grant/GettyKim Raver’s character, Dr. Teddy Altman, has mastered the complexities of cardiothoracic surgery. But off-screen, Raver excels at the art of keeping her private life under the radar.The actress has been married to her French director husbandManu Boyersince 2000, and she chooses to keep the intimate details of their relationship to herself.Asked about their first meeting, Raver toldWomen’s Health, “I met him in New York, in a swimming pool. That first meeting is kind of sacred, so I think I want to keep it to myself.“The couple have two sons: Luke West and Leo Kipling.

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Kim Raver & Manu Boyer

Manu Boyer and Kim Raver attend Lifetime’s Female Directors and Leading Actresses 2019 Winter Television Critics Association Press Tour at The Langham Huntington on Feb. 10, 2019, in Pasadena, Calif.Jesse Grant/Getty

Kim Raver’s character, Dr. Teddy Altman, has mastered the complexities of cardiothoracic surgery. But off-screen, Raver excels at the art of keeping her private life under the radar.

The actress has been married to her French director husbandManu Boyersince 2000, and she chooses to keep the intimate details of their relationship to herself.

Asked about their first meeting, Raver toldWomen’s Health, “I met him in New York, in a swimming pool. That first meeting is kind of sacred, so I think I want to keep it to myself.”

The couple have two sons: Luke West and Leo Kipling.

06of 22Kevin McKidd and Danielle SavreDanielle Savre and Kevin McKidd attend Walt Disney Company Post-Emmys Celebration on Jan. 15, 2024, in Los Angeles.Stewart Cookt/Disney via GettyKevin McKidd— a.k.a. Dr. Owen Hunt — has been datingStation 19actressDanielle Savresince at least June 2023.They made their red carpet debut in November 2023 and stepped out together again two months later at the 2023 Emmy Awards Celebration.There, McKidd opened up to PEOPLE about his new relationship, saying, “We’re really happy and she’s an amazing human being, so I feellucky on many levels in my life right now.”The actor was previously married to ex-wifeArielle Goldrath, with whom he sharestwo children: Aiden and Nava. Additionally, he was married to ex-wifeJane Parkerfor 17 years, and they welcomed two children, daughter Iona and son Joseph.

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Kevin McKidd and Danielle Savre

Danielle Savre and Kevin McKidd attend Walt Disney Company Post-Emmys Celebration on Jan. 15, 2024, in Los Angeles.Stewart Cookt/Disney via Getty

Stewart Cookt/Disney via Getty

Kevin McKidd— a.k.a. Dr. Owen Hunt — has been datingStation 19actressDanielle Savresince at least June 2023.

They made their red carpet debut in November 2023 and stepped out together again two months later at the 2023 Emmy Awards Celebration.

There, McKidd opened up to PEOPLE about his new relationship, saying, “We’re really happy and she’s an amazing human being, so I feellucky on many levels in my life right now.”

The actor was previously married to ex-wifeArielle Goldrath, with whom he sharestwo children: Aiden and Nava. Additionally, he was married to ex-wifeJane Parkerfor 17 years, and they welcomed two children, daughter Iona and son Joseph.

07of 22James Pickens Jr. & Gina TaylorJames Pickens Jr. and wife Gina Taylor Pickens attend a Pre-Emmy Food Tasting Mixer on Sept. 18, 2013, in Los Angeles.Maury Phillips/WireImageJames Pickens Jr. has been in a relationship for the entire time he’s been playing Dr. Richard Webber onGrey’s Anatomy.Though not much information is known about his wife, Gina Taylor is a credited actress, having worked in films such asDeliver Us From Eva, and is featured on soundtracks forThe Lion King 1 1/2as well asSing Along Songs: Brother Bear,per IMDb.The two were married in 1984 and share two children — Gavyn Picken and Carl Tharps.

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James Pickens Jr. & Gina Taylor

James Pickens Jr. and wife Gina Taylor Pickens attend a Pre-Emmy Food Tasting Mixer on Sept. 18, 2013, in Los Angeles.Maury Phillips/WireImage

James Pickens Jr. has been in a relationship for the entire time he’s been playing Dr. Richard Webber onGrey’s Anatomy.

Though not much information is known about his wife, Gina Taylor is a credited actress, having worked in films such asDeliver Us From Eva, and is featured on soundtracks forThe Lion King 1 1/2as well asSing Along Songs: Brother Bear,per IMDb.

The two were married in 1984 and share two children — Gavyn Picken and Carl Tharps.

08of 22Debbie Allen & Norm NixonDebbie Allen and Norm Nixon attend the 300th Episode Celebration for ABC’s ‘Grey’s Anatomy’ on Nov. 4, 2017, in Los Angeles.Amanda Edwards/WireImageDebbie Allen’sGrey’s Anatomycharacter Catherine Avery found love with Richard Webber, but off-screen, the actress has been married to her husband,Norm Nixon, for over four decades.Nixon is a retired NBA player turned actor and producer, and the pair met in 1979 while filmingThe Fish That Saved Pittsburgh.Although they were just friends at first, they eventually got together and tied the knot on April 27, 1984.Over the years, Allen has been candid about the ups and downs of marriage. In September 2024, she told PEOPLE that the pair have “hit some rocks and hit some walls” during their marriage.“But at the end of the day, we really love each other and we sleep together every night and we love our family,” she said.The pair sharethree children:DeVaughn, Normon Jr. and Vivian.

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Debbie Allen & Norm Nixon

Debbie Allen and Norm Nixon attend the 300th Episode Celebration for ABC’s ‘Grey’s Anatomy’ on Nov. 4, 2017, in Los Angeles.Amanda Edwards/WireImage

Amanda Edwards/WireImage

Debbie Allen’sGrey’s Anatomycharacter Catherine Avery found love with Richard Webber, but off-screen, the actress has been married to her husband,Norm Nixon, for over four decades.

Nixon is a retired NBA player turned actor and producer, and the pair met in 1979 while filmingThe Fish That Saved Pittsburgh.Although they were just friends at first, they eventually got together and tied the knot on April 27, 1984.

Over the years, Allen has been candid about the ups and downs of marriage. In September 2024, she told PEOPLE that the pair have “hit some rocks and hit some walls” during their marriage.

“But at the end of the day, we really love each other and we sleep together every night and we love our family,” she said.

The pair sharethree children:DeVaughn, Normon Jr. and Vivian.

09of 22Jason Winston George & Vandana KhannaJason George and Vandana Khanna attend The Trevor Project’s 2016 TrevorLIVE LA at The Beverly Hilton Hotel on Dec. 4, 2016, in Beverly Hills, Calif.Tommaso Boddi/GettyJason Winston George’sGrey’s Anatomycharacter Ben Warren may be devoted to Miranda Bailey — but in real life, the actor is very much in love with his wife, Vandana Khanna. The pair met in college and wed in 1999.So what’s been the secret to their long-lasting marriage?“We fight fair,” he toldSteve Harveyin November 2017. “You’re gonna have fights because if you don’t have fights, you’re not being honest. So when you fight, you’ve gotta be fair about it.“Asked to explain further, George elaborated, saying, “When you settle it, don’t say it’s settled if it’s not, and then bring it up again six months later. When you settle it, it’s settled. Right?”

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Jason Winston George & Vandana Khanna

Jason George and Vandana Khanna attend The Trevor Project’s 2016 TrevorLIVE LA at The Beverly Hilton Hotel on Dec. 4, 2016, in Beverly Hills, Calif.Tommaso Boddi/Getty

Jason Winston George’sGrey’s Anatomycharacter Ben Warren may be devoted to Miranda Bailey — but in real life, the actor is very much in love with his wife, Vandana Khanna. The pair met in college and wed in 1999.

So what’s been the secret to their long-lasting marriage?

“We fight fair,” he toldSteve Harveyin November 2017. “You’re gonna have fights because if you don’t have fights, you’re not being honest. So when you fight, you’ve gotta be fair about it.”

Asked to explain further, George elaborated, saying, “When you settle it, don’t say it’s settled if it’s not, and then bring it up again six months later. When you settle it, it’s settled. Right?”

10of 22Scott Speedman & Lindsay Rae HoffmanScott Speedman and Lindsay Rae Hofmann at an event for ‘Grey’s Anatomy.'.Stewart Cook via GettyScott Speedman’s character Dr. Nick Marsh has had his eyes on Meredith Grey since he arrived at Grey Sloan as a patient. But when he takes his scrubs off and heads home, Speedman is focused on his fiancée,Lindsay Rae Hofmann.The pair have been romantically linked since 2017 andgot engaged in 2023. Hofmann is more than just Speedman’s partner, though — she might just be his lucky charm for getting cast on popular shows.“She started watchingYou,and then I ended up on that show,” the actor toldEsquirein October 2021. “She started binge-watchingGrey’s Anatomyon Netflix during the pandemic, and here I am. Whatever she seems to watch, I seem to end up on.“Speedman and Hofmann became parents in October 2021 when they welcomeddaughter Pfeiffer Lucia. In September 2024, they became a family of four whenson Indy Roywas born.

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Scott Speedman & Lindsay Rae Hoffman

Scott Speedman and Lindsay Rae Hofmann at an event for ‘Grey’s Anatomy.'.Stewart Cook via Getty

Scott Speedman’s character Dr. Nick Marsh has had his eyes on Meredith Grey since he arrived at Grey Sloan as a patient. But when he takes his scrubs off and heads home, Speedman is focused on his fiancée,Lindsay Rae Hofmann.

The pair have been romantically linked since 2017 andgot engaged in 2023. Hofmann is more than just Speedman’s partner, though — she might just be his lucky charm for getting cast on popular shows.

“She started watchingYou,and then I ended up on that show,” the actor toldEsquirein October 2021. “She started binge-watchingGrey’s Anatomyon Netflix during the pandemic, and here I am. Whatever she seems to watch, I seem to end up on.”

Speedman and Hofmann became parents in October 2021 when they welcomeddaughter Pfeiffer Lucia. In September 2024, they became a family of four whenson Indy Roywas born.

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Emma McIntyre/WireImage

During an October 2022 appearance on theThe Jennifer Hudson Show, Shum Jr. shared that their first date was a trip to the theaters to seeDreamgirlstogether.

“We both cried and it was just such a beautiful experience because after that we just talked about you,” he told hostJennifer Hudson. “It really kinda brought us together and we opened up about a lot of things and it was just such a beautiful first date.”

Shum Jr. and Rabara got engaged in October 2014 andtied the knotin November 2015. In March 2019, they welcomed their first child,daughter Xia.

In addition to sharing a child, Shum Jr. and Rabara both have a passion for acting and dancing. While they both appeared onGlee, Rabara additionally had a role in 2009’s17 Again. She has also lent her voice to the character Peridot for theSteven Universefranchise on Cartoon Network.

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Patrick Dempsey & Jillian Dempsey

Patrick Dempsey and Jillian Dempsey attend the Porsche Design Celebrates Festival of Watches on Sept. 14, 2014, in Beverly Hills, Calif.Charley Gallay/Getty

Patrick Dempseyhas been stealing the hearts ofGrey’s Anatomyfans since day one, portraying Dr. Derek Shepherd, a.k.a “McDreamy.” But off-screen, he is devoted to his wife,Jillian.

Dempsey’s run-in with his wife was written in the stars — or, at least, in an appointment book.

At the time of their meeting in 1994, Jillian, who owned a hair salon, had an employee who had a knack for jotting down celebrity names in the appointment book as a joke. So, when she saw her future husband’s name on the list of clients, she thought it was another ruse.

However, when the actor walked in, Jillian was pleasantly surprised. “I was shocked,” she recalled. “But at the same time, I was happy because he was so cute.”

At the time, both parties were in relationships and didn’t get together until 1997. Jillian moved in three months after their first date and the couple wed in 1999.

Beautiful as their love story has been, the Dempseys have been honest about the tougher times in their marriage, including theirnear-split in 2015.

“Our marriage wasnot something I was prepared to let go of,” Patrick told PEOPLE in September 2016. “I didn’t feel like we had done all the work. And we both wanted to do that work. That’s where it started.”

13of 22Justin Chambers & Keisha ChambersJustin Chambers and Keisha Chambers during The 37th Annual NAACP Image Awards - Arrivals at Shrine Auditorium in Los Angeles.Jason Merritt/FilmMagicAlex Karev may have beenconflicted between his past love, Izzie Stevens, and more recent love Jo Wilson, but in real life,Justin Chambers’ heart has belonged to one woman — his wife, Keisha — for upwards of 30 years.The two met when Chambers was working as a model in the early ’90s and his wife was a booking agent. They got married in 1993 and sharefive kids: Isabella, Maya, Kaila, Eva and Jackson.During a 2007 conversation withGood Housekeeping, Chambers opened up about his long-term relationship with his soulmate, saying, “We’ve been together for so long that I really don’t know any other way to be.““Every relationship has its ups and downs, but I’m glad I get to go through the ups and downs with her,” he said. “I just feel really fortunate to have found someone who will be my partner on this journey.”

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Justin Chambers & Keisha Chambers

Justin Chambers and Keisha Chambers during The 37th Annual NAACP Image Awards - Arrivals at Shrine Auditorium in Los Angeles.Jason Merritt/FilmMagic

Alex Karev may have beenconflicted between his past love, Izzie Stevens, and more recent love Jo Wilson, but in real life,Justin Chambers’ heart has belonged to one woman — his wife, Keisha — for upwards of 30 years.

The two met when Chambers was working as a model in the early ’90s and his wife was a booking agent. They got married in 1993 and sharefive kids: Isabella, Maya, Kaila, Eva and Jackson.

During a 2007 conversation withGood Housekeeping, Chambers opened up about his long-term relationship with his soulmate, saying, “We’ve been together for so long that I really don’t know any other way to be.”

“Every relationship has its ups and downs, but I’m glad I get to go through the ups and downs with her,” he said. “I just feel really fortunate to have found someone who will be my partner on this journey.”

14of 22Katherine Heigl & Josh KelleyJosh Kelley and Katherine Heigl attend the 2017 CMT Music Awards on June 7, 2017, in Nashville.J. Merritt/FilmMagicKatherine Heigl(who played Izzie Stevens) andJosh Kelley’s meet-cute is the ultimate Hollywood love story: The two met when the actress starred in the musician’s “Only You” video. The rest was history.The stars began dating in 2005 and got married in aprivate ceremony in Utahin 2007.To celebrate their 10th anniversary in 2017, Heigl posted a candidInstagramcaption about their relationship, writing, “I gotta be honest. There have beenmoments where I didn’t think we’d make it,” she wrote.“The more time I spend with this guy the more deeply I begin to understand that he is the best of me,” she added. “When the whole world falls into disarray and nothing makes sense to me he is my shelter, my safe harbor.“Heigl continued, “When self-doubt and self-loathing creep into my soul he is my champion, my number-one fan.“The two havethree children: Naleigh, Adalaide Marie Hope and Joshua.

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Katherine Heigl & Josh Kelley

Josh Kelley and Katherine Heigl attend the 2017 CMT Music Awards on June 7, 2017, in Nashville.J. Merritt/FilmMagic

J. Merritt/FilmMagic

Katherine Heigl(who played Izzie Stevens) andJosh Kelley’s meet-cute is the ultimate Hollywood love story: The two met when the actress starred in the musician’s “Only You” video. The rest was history.

The stars began dating in 2005 and got married in aprivate ceremony in Utahin 2007.

To celebrate their 10th anniversary in 2017, Heigl posted a candidInstagramcaption about their relationship, writing, “I gotta be honest. There have beenmoments where I didn’t think we’d make it,” she wrote.

“The more time I spend with this guy the more deeply I begin to understand that he is the best of me,” she added. “When the whole world falls into disarray and nothing makes sense to me he is my shelter, my safe harbor.”

Heigl continued, “When self-doubt and self-loathing creep into my soul he is my champion, my number-one fan.”

The two havethree children: Naleigh, Adalaide Marie Hope and Joshua.

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T.R. Knight & Patrick Leahy

T.R. Knight and husband Patrick Leahy attend the after party for ‘Romeo And Juliet’ Off Broadway opening night production at Pangea on Oct. 16, 2013, in New York City.Bruce Glikas/FilmMagic

T.R. Knight— whose beloved character George O’Malley exited the show in season 6 — has been locked down with his longtime beau, Patrick Leahy, for more than a decade.

“Ten years ago, @bridgeteverett @zshaffer1 and @jasoneagan made meeting this magnificent human possible. My goal for the next ten? Keep trying to deserve him,” Knight wrote onInstagram.

He shared the same sentiment under pictures commemorating their 10th wedding anniversary in October 2023 onInstagram, writing, “Ten years ago yesterday, I got married to this extraordinary man.Never dreamed this could happenin my lifetime.”

He added, “We hold close to our hearts all those that never had- nor will have- this right.”

16of 22Jesse Williams & Ciarra PardoJesse Williams and Ciarra Pardo attend the 4th Annual Fifteen Percent Pledge Gala on Feb. 1, 2025, in Los Angeles.UNIQUE NICOLE/AFP via GettySorryGrey’sfans, but it appears everyone’s favorite plastic surgeon,Jesse Williams’ Jackson Avery, is off the market.The actor and activist was spotted strolling the streets of New York City hand-in-hand with Ciarra Pardo in June 2022. They’ve kept their romance low-key since, though they’ve attended several events together, including the 4th Annual Fifteen Percent Pledge Gala in February 2025.According to herInstagram bio, Pardo is the co-founder of N4XT Experiences — a premier and global event experience company — and is the current president of L.A. Fashion Week. She also previously served as chief creative officer of Rihanna’s Fenty Corp from 2014 to 2019, per herLinkedIn.

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Jesse Williams & Ciarra Pardo

Jesse Williams and Ciarra Pardo attend the 4th Annual Fifteen Percent Pledge Gala on Feb. 1, 2025, in Los Angeles.UNIQUE NICOLE/AFP via Getty

UNIQUE NICOLE/AFP via Getty

SorryGrey’sfans, but it appears everyone’s favorite plastic surgeon,Jesse Williams' Jackson Avery, is off the market.

The actor and activist was spotted strolling the streets of New York City hand-in-hand with Ciarra Pardo in June 2022. They’ve kept their romance low-key since, though they’ve attended several events together, including the 4th Annual Fifteen Percent Pledge Gala in February 2025.

According to herInstagram bio, Pardo is the co-founder of N4XT Experiences — a premier and global event experience company — and is the current president of L.A. Fashion Week. She also previously served as chief creative officer of Rihanna’s Fenty Corp from 2014 to 2019, per herLinkedIn.

17of 22Kate Walsh & Andrew NixonAndrew Nixon and Kate Walsh attend a screening of season 3 of ‘Emily In Paris’ held on Dec. 15, 2022, in New York City.Nina Westervelt/Variety via GettyKate Walsh, who portrayed Addison Montgomery onGrey’s AnatomyandPrivate Practice, has love off-screen with her fiancé,Andrew Nixon.Walsh and Nixon met in an unbelievable way: on a ship just before the pandemic.“We met, as one does, on a NatGeo expedition to Antarctica,” she shared during a January 2023 appearance onThe Kelly Clarkson Show. Of the trip, she joked, “[Saw the] penguins, check. Ice, check. Whales, check. Man, check.“Like many of her castmates, Walsh has kept her relationship off the grid, but she did accidentally reveal she and Nixon were engaged during an Instagram Live with her longtime friend andPrivate Practicecostar Amy Brenneman in October 2022.Walsh was previously married to studio executive Alex Young. The two divorced in 2010.

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Kate Walsh & Andrew Nixon

Andrew Nixon and Kate Walsh attend a screening of season 3 of ‘Emily In Paris’ held on Dec. 15, 2022, in New York City.Nina Westervelt/Variety via Getty

Nina Westervelt/Variety via Getty

Kate Walsh, who portrayed Addison Montgomery onGrey’s AnatomyandPrivate Practice, has love off-screen with her fiancé,Andrew Nixon.

Walsh and Nixon met in an unbelievable way: on a ship just before the pandemic.

“We met, as one does, on a NatGeo expedition to Antarctica,” she shared during a January 2023 appearance onThe Kelly Clarkson Show. Of the trip, she joked, “[Saw the] penguins, check. Ice, check. Whales, check. Man, check.”

Like many of her castmates, Walsh has kept her relationship off the grid, but she did accidentally reveal she and Nixon were engaged during an Instagram Live with her longtime friend andPrivate Practicecostar Amy Brenneman in October 2022.

Walsh was previously married to studio executive Alex Young. The two divorced in 2010.

18of 22Chyler Leigh & Nathan WestChyler Leigh and Nathan West arrive at the 2017 GLSEN Respect Awards at the Beverly Wilshire Four Seasons Hotel on Oct. 20, 2017, in Beverly Hills, Calif.Gregg DeGuire/WireImageChyler Leigh(a.k.a. Lexie Grey) has been married to her husband, Nathan West, since 2002.In addition to sharing three kids — son Noah Wilde and daughters Taelyn Leigh andAnniston Kae— the two also share a passion for music.In fact, Leigh made her singing debut in 2017, collaborating with her husband on a song titled “Nowhere.““There’s a lot of times right now with our careers where there’sa lot missed opportunities to be together,” West told PEOPLE of the song’s inspiration. “We find ourselves going a couple of weeks sometimes without really having a chance just to connect.““When I was writing ‘Nowhere,’ that’s what I was thinking about,” she continued. “While I was thinking of her she was thinking of me. It’s special because love knows no boundaries.”

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Chyler Leigh & Nathan West

Chyler Leigh and Nathan West arrive at the 2017 GLSEN Respect Awards at the Beverly Wilshire Four Seasons Hotel on Oct. 20, 2017, in Beverly Hills, Calif.Gregg DeGuire/WireImage

Chyler Leigh(a.k.a. Lexie Grey) has been married to her husband, Nathan West, since 2002.

In addition to sharing three kids — son Noah Wilde and daughters Taelyn Leigh andAnniston Kae— the two also share a passion for music.

In fact, Leigh made her singing debut in 2017, collaborating with her husband on a song titled “Nowhere.”

“There’s a lot of times right now with our careers where there’sa lot missed opportunities to be together,” West told PEOPLE of the song’s inspiration. “We find ourselves going a couple of weeks sometimes without really having a chance just to connect.”

“When I was writing ‘Nowhere,’ that’s what I was thinking about,” she continued. “While I was thinking of her she was thinking of me. It’s special because love knows no boundaries.”

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Jessica Capshaw & Christopher Gavigan

Capshaw, who played Arizona Robbins, tends to keep her marriage out of the spotlight. She married entrepreneur and co-founder of The Honest Company, Christopher Gavigan, in 2004.

They havefour children: Luke, Eve, Poppy and Josephine.

20of 22Sarah Drew & Peter LanferActress Sarah Drew and her husband Peter Lanfer attend the 2018 Creative Arts Emmy Awards - Day 1 at Microsoft Theater on Sept. 8, 2018, in Los Angeles.Paul Archuleta/FilmMagicLong before we knew her as the eccentric April Kepner onGrey’s Anatomy,Sarah Drewmarried her husband, Peter Lanfer, in 2002. The pair sharetwo children:Micah Emmanueland Hannah Mali Rose.Her kids have grown up to be her support system, with Drew even revealing in January 2025 that her son helped herprocess the “pain” of leavingGrey’s Anatomy.“I’ve had Micah say to me, ‘What’s so great is that if you were still onGrey’s, you would not be able to be onMistletoe Murders,’ " she said on theBetween Us Momspodcast, referring to her new show.She continued, “And I was like, ‘You’re right. You’re right.’ And this is the joy that came out of that closed door. What I’m living in and experiencing right now. So there you go.”

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Sarah Drew & Peter Lanfer

Actress Sarah Drew and her husband Peter Lanfer attend the 2018 Creative Arts Emmy Awards - Day 1 at Microsoft Theater on Sept. 8, 2018, in Los Angeles.Paul Archuleta/FilmMagic

Long before we knew her as the eccentric April Kepner onGrey’s Anatomy,Sarah Drewmarried her husband, Peter Lanfer, in 2002. The pair sharetwo children:Micah Emmanueland Hannah Mali Rose.

Her kids have grown up to be her support system, with Drew even revealing in January 2025 that her son helped herprocess the “pain” of leavingGrey’s Anatomy.

“I’ve had Micah say to me, ‘What’s so great is that if you were still onGrey’s, you would not be able to be onMistletoe Murders,’ " she said on theBetween Us Momspodcast, referring to her new show.

She continued, “And I was like, ‘You’re right. You’re right.’ And this is the joy that came out of that closed door. What I’m living in and experiencing right now. So there you go.”

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Kelly McCreary & Pete Chatmon

Pete Chatmon and Kelly McCreary attend the private reception celebrating the opening of “Kwame Brathwaite: Celebrity and The Everyday” at Philip Martin Gallery on Nov. 3, 2018, in Los Angeles.Colin Gray/Getty

Married life was quite the rollercoaster forKelly McCreary’s character, Dr. Maggie Pierce, before she exited the show in 2023. But in real life, it’s been more smooth sailing.

In fact, the show served as the perfect conduit for the actress and her director husband,Pete Chatmon, as the two met on set.

McCreary and Chatmon got married in an intimate seaside wedding ceremony in 2019 and shared images of their big day with fans onInstagram.

The couple welcomed their first child, daughterIndigo Wren, in October 2021.

22of 22Giacomo Gianniotti & Nichole GustafsonNichole Gustafson and Giacomo Gianniotti attend Ending Youth Homelessness: A Benefit for My Friend’s Place at Hollywood Palladium on April 6, 2019, in Los Angeles.Vivien Killilea/GettyFor their2019 wedding,Giacomo Gianniotti, who portrayed Andrew DeLuca before his departure from the show, and his bride, Nichole Gustafson, went back to the actor’s place of birth: Rome.The couple said “I do” at Villa Pocci, which sits on a lake and overlooks Castel Gandolfo, a year after theGrey’sheartthrob proposed.In February 2024, the actor shared a tribute to his “forever Valentine” onInstagram.“Whether it’s in the middle of Piazza Navona at 5am or our kitchen, I’ll always dance with you,” he wrote.

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Giacomo Gianniotti & Nichole Gustafson

Nichole Gustafson and Giacomo Gianniotti attend Ending Youth Homelessness: A Benefit for My Friend’s Place at Hollywood Palladium on April 6, 2019, in Los Angeles.Vivien Killilea/Getty

For their2019 wedding,Giacomo Gianniotti, who portrayed Andrew DeLuca before his departure from the show, and his bride, Nichole Gustafson, went back to the actor’s place of birth: Rome.

The couple said “I do” at Villa Pocci, which sits on a lake and overlooks Castel Gandolfo, a year after theGrey’sheartthrob proposed.

In February 2024, the actor shared a tribute to his “forever Valentine” onInstagram.

“Whether it’s in the middle of Piazza Navona at 5am or our kitchen, I’ll always dance with you,” he wrote.

source: people.com